Endocrine Abstracts

Many patients continue complaining of subjective symptoms of hypothyroidism despite being on adequate doses of levothyroxine. There are about 14 studies involving T3+T4 combination including 7 which were rigorously conducted. Majority of them (11 studies) did not show any benefit of combination therapy. But our local experience has been a little different. We looked at small cohort of 15 patients who were on combination T3+T4 for more than 6 months and were asked...

Many patients continue complaining of subjective symptoms of hypothyroidism despite being on adequate doses of levothyroxine. There are about 14 studies involving T3+T4 combination including 7 which were rigorously conducted. Majority of them (11 studies) did not show any benefit of combination therapy. But our local experience has been a little different. We looked at small cohort of 15 patients who were on combination T3+T4 for more than 6 months and were asked...

Amiodarone is commonly prescribed anti-arrhythmic drug which can lead to thyroid dysfunction manifesting as either hypothyroidism or hyperthyroidism. This clinical case of amiodarone induced thyrotoxicosis is being reported to highlight the challenges faced during its management. A 72-year-old gentleman was admitted with history of recurrent falls. He had past medical history of non-ischemic cardiomyopathy, CRT, atrial fibrillation, vascular dementia, osteoporosis, primary hyp...

Ectopic ACTH is an infrequent cause of Cushing’s syndrome which can be severe in its presentation and needs immediate management to in order to prevent the complications associated with severe hypercortisolism. This case of ectopic ACTH secretion is being reported who presented clinically as Cushing’s syndrome and later diagnosed to have small cell carcinoma of lung. A 62-year-old previously normally fit and well lady presented with 1-month history of feeling unwell,...

Adrenal incidentalomas is a common referral to endocrine department. We retrospectively looked at the number of referrals to the endocrine services with it over 1 year and their eventual outcomes. There were a total of 37 patients referred with adrenal incidentalomas to our department out of which 28 patients (76%) were non secretory, while 1 (3%) had catecholamine excess. 1 (3%) had mixed cortisol + catecholamine excess. 7(19%) patients either did n...

Primary Hyperparathyroidism is one of the common endocrine disorders seen in an endocrine clinic. We retrospectively analysed patients referred with primary hyperparathyroidism over 1 yr (Oct 2013 - Sept 2014) and followed them over next 30 months. Patients with isolated secondary hyperparathyroidism were excluded. Few had secondary hyperparathyroidism in addition to primary hyperparathyroidism.50 patients with primary hyperparathy...

Adrenal incidentalomas is a common referral to endocrine department. We retrospectively looked at the number of referrals to the endocrine services with it over 1 year and their eventual outcomes. There were a total of 37 patients referred with adrenal incidentalomas to our department out of which 28 patients (76%) were non secretory, while 1 (3%) had catecholamine excess. 1 (3%) had mixed cortisol + catecholamine excess. 7(19%) patients either did n...

Primary Hyperparathyroidism is one of the common endocrine disorders seen in an endocrine clinic. We retrospectively analysed patients referred with primary hyperparathyroidism over 1 yr (Oct 2013 - Sept 2014) and followed them over next 30 months. Patients with isolated secondary hyperparathyroidism were excluded. Few had secondary hyperparathyroidism in addition to primary hyperparathyroidism.50 patients with primary hyperparathy...